Healthcare News
Clinical Application of Mesenchymal Stem Cells in Orthopaedics and Traumatology in Daily Practice
Mesenchymal stem cells (MSCs) have been widely used in preclinical and clinical orthopaedic and traumatology studies (1). Compared to other cell therapies, MSCs have a variety of characteristics, such as a lower risk of teratoma than pluripotent stem cells, stemness potency, targeted therapy through chemo-attraction, ease of isolation, and rapid proliferation (2). However, the application from bench to bedside requires a standardized procedure for its administration (1).
Source: ScienceDirect
Short-Term Clinical Outcomes of Platelet-Rich Plasma Injections in Patients With Rotator Cuff Tendinopathy and Partial-Thickness Rotator Cuff Tears
Platelet-rich plasma (PRP) has been increasingly applied for rotator cuff pathology; however, clinical evidence regarding its short-term efficacy remains limited. This study evaluated the effectiveness of a single PRP injection for rotator cuff injury.
Source: Cureus
Comparative Outcomes of Hip Arthroscopy-Assisted Surgery and the Direct Anterior Approach for Pipkin Type I and II Femoral Head Fractures
Comparative evidence regarding the direct anterior approach and hip arthroscopyā€“assisted surgery for Pipkin type I and II fractures remains limited. This study compares these minimally invasive strategies and evaluates whether fragment excision or internal fixation yields superior functional outcomes.
Source: ScienceDirect
Platelet-Rich Plasma in the Treatment of Knee Osteoarthritis: A Bibliometric Analysis of Global Research Trends
Knee osteoarthritis (OA) represents a major cause of pain and disability among older adults. Platelet-rich plasma (PRP) has emerged as a promising biologic therapy aimed at modulating inflammation and promoting cartilage repair. As the clinical use of PRP has expanded, a rapidly growing body of literature has developed examining its efficacy and mechanisms of action in knee OA. Bibliometric analysis provides a useful method to evaluate research productivity, collaborative networks, and emerging trends within a scientific field.
Source: Orthopedic Reviews
Broken Hip Recovery
Recovering from a broken hip typically involves surgery followed by physical therapy to restore mobility and strength. Early movement after surgery is crucial for regaining function and preventing complications. While pain usually lessens after four to six weeks, it can take up to a year to fully recover from a broken hip.
Source: Verywell health
One of the world`s most common knee surgeries does not help and may even be harmful
Trimming a degenerated meniscus, or partial meniscectomy, is one the most common orthopedic surgeries in the world. Partial meniscectomy does not improve patient symptoms or function, reveals a 10-year follow-up of the FIDELITY, a placebo-surgery controlled trial published in the New England Journal of Medicine.
Source: Medical Xpress
Biological Treatment in Meniscus Injury
Meniscal injuries, common in sports, often cause knee pain and instability. The meniscus plays a key role in pressure distribution and joint stability, making its repair essential. Treatments range from conservative approaches to surgical interventions, with growing interest in biological factors such as growth factors, mesenchymal stem cells, platelet-rich plasma, fibrin clot, and tenocyte to enhance healing. This review compares the effects of these biological agents in meniscal repair, examining their mechanisms, limitations, and clinical outcomes.
Platelet-Rich Plasma Injections Prior to Total Shoulder Arthroplasty May be Associated with Increased Infection Risk in a Time-Dependent Manner
While platelet-rich plasma (PRP) is widely used for managing shoulder pathology, its implications when administered shortly before total shoulder arthroplasty (TSA) are unclear. This study investigates postoperative outcomes associated with PRP use within one year of TSA, with a focus on infection and revision rates.
Source: ScienceDirect
Clinical Outcomes of Arthroscopic Hip Labral Reconstruction Versus Repair in the Primary Setting: A Systematic Review and Meta-Analysis
Advancements in understanding the acetabular labrum's role in hip biomechanics have emphasized preserving its native anatomy. However, severe labral pathology may make labral repair unfeasible in certain cases. The primary aim of the present study is to review existing literature comparing clinical outcomes of arthroscopic hip labral reconstruction versus repair in the primary setting.
Source: ScienceDirect
Short-Term Functional Outcomes in Patients Undergoing Primary Total Knee Arthroplasty According to Their Body Mass Index
This study aimed to evaluate the association between body mass index (BMI) and short-term outcomes following primary unilateral total knee arthroplasty (TKA), including functional improvement, perioperative variables, and postoperative complications.
Source: Cureus
